SENIOR FULL-STACK SOFTWARE ENGINEER - Philogen Spa

Open positions Job Title: SENIOR FULL-STACK SOFTWARE ENGINEER Location: Milano - Italy Department: Others About Philogen Philogen S.p.A. is a biotechnology company dedicated to developing targeted products for the imaging and treatment of life-threatening diseases, with a strategic focus on oncology. Our mission is to translate cutting-edge scientific innovation into effective therapies that improve patients’ lives. Position Overview At Philogen, we are building a small, high-impact engineering team focused on transforming core business processes into secure, production-grade software and AI systems. These systems support clinical operations, R&D, finance, and corporate functions in a highly regulated environment. We are looking for a Senior Full-Stack Software Engineer to take substantial ownership of the platform, its infrastructure, and its production deployments. This is a full-stack role in the literal sense: you will work across backend services, cloud infrastructure, deployment automation, frontend applications, identity, authorization, data systems, and isolated AI-agent execution environments. Backend and infrastructure expertise are baseline requirements. Strong frontend expertise is an additional advantage. What You Will Do — Build and operate Python services, APIs, CLIs, and full-stack workflows using TypeScript, React, and Next.js. Provision and run GCP and Kubernetes infrastructure through Pulumi, including databases, object storage, networking, secrets, deployments, and recovery procedures. Build secure execution environments for AI agents, covering sandbox lifecycle, tool access, workload identity, network isolation, resource limits, and persistent sessions. Integrate model providers and agent SDKs, including streaming, tool calls, cancellation, and long-running execution. Implement authentication, RBAC, least-privilege access, auditability, and compliance requirements as enforceable technical controls. Own production reliability across application and infrastructure layers through testing, observability, performance analysis, incident diagnosis, and safe deployments. Design and ship agent-driven user experiences spanning chat, files, interactive tools, and data-intensive workflows. What We Are Looking For 5+ years of full-time software engineering experience in production environments. Strong Python and TypeScript skills and the ability to work effectively across frontend and backend code. Strong SQL and database fundamentals, including schema evolution, transactions, concurrency, access control, and operational recovery. Production experience with Kubernetes and at least one major cloud platform, preferably GCP or AWS. Experience with infrastructure-as-code, preferably Pulumi or Terraform. Strong understanding of containers, Linux, networking, secrets, service identities, and deployment automation. Experience designing authentication, authorization, RBAC, and audit-sensitive workflows. Experience leading substantial deployments or owning production services after release. Strong judgment regarding least privilege, data residency, encryption, sensitive-data handling, and secure software design. High daily engagement with modern AI development tools such as Claude Code and Codex. Ability to work with non-technical stakeholders and translate operational needs into reliable software. Nice to Have Deep frontend expertise with TypeScript, React, Next.js, streaming interfaces, and complex interactive applications. Experience building developer tools, command-line applications, agent harnesses, or AI-assisted coding environments. Experience with healthcare, biotechnology, pharmaceuticals, finance, or similarly regulated systems. Knowledge of HIPAA, GDPR, GxP, audit-trail requirements, or regulated software validation. Experience delivering infrastructure or software platforms for pharmaceutical or healthcare customers. Familiarity with analytical data systems, knowledge graphs, ontologies, or data-integration platforms. Experience designing and testing controls for software subject to formal security, privacy, or regulatory review. Education Master’s degree in Computer Science, Software Engineering, Mathematics, Engineering, or a related technical field. Equivalent substantial professional experience may be considered. A strong academic background with international exposure. What We Offer Full-time employment. Gross annual salary ranging from €60,000 to €100,000 RAL. Positioning within the salary range will be determined based on objective and neutral criteria, taking into account the candidate’s skills, experience, and the level of responsibility associated with the role, as assessed throughout the selection process. Broad technical ownership across product, infrastructure, security, and deployment. The opportunity to build and shape core AI systems used across scientific and operational workflows. Direct exposure to leadership and high-impact projects across the organization. A fast-moving, engineering-driven environment focused on production delivery rather than prototypes. Job Location Milan, Italy. We invite interested candidates to submit their applications expressly authorizing the processing of personal data in accordance with Legislative Decree 196/2003. Our recruitment adheres to the provisions of Legislative Decree 198/2006, and we welcome applications from candidates of any gender orientation or expression, sexual orientation, age, ethnicity, or religious belief. In compliance with Directive (EU) 2023/970 and Italian Legislative Decree No. 96 of 7 May 2026, this job advertisement has been drafted using gender-neutral criteria. Open Position careers search Search content Clear department Select content Department Others (7) Clinical (2) QA (1) QC & Analytical (1) location Select content Location Siena - Italy (7) Milano - Italy (5) Zurich – Switzerland (1) 17 July 2026 LIFE SCIENCES SOLUTIONS ENGINEER Department: Others Location: Milano - Italy Read more 17 July 2026 SENIOR FULL-STACK SOFTWARE ENGINEER Department: Others Location: Milano - Italy Read more 17 July 2026 DATA & AI INTERN Department: Others Location: Milano - Italy Read more 5 June 2026 EXECUTIVE ASSISTANT Department: Others Location: Siena - Italy Read more 5 June 2026 INTERN FINANCIAL OFFICE Department: Others Location: Siena - Italy Read more 5 June 2026 JUNIOR CLINICAL RESEARCH ASSOCIATE Department: Clinical Location: Siena - Italy, Milano - Italy Read more 5 June 2026 DEPUTY CHIEF MEDICAL OFFICER Department: Clinical Location: Siena - Italy, Milano - Italy, Zurich – Switzerland Read more 5 June 2026 GRADUATES IN BIOLOGY, BIOTECHNOLOGY, CHEMISTRY Department: QC & Analytical, QA Location: Siena - Italy Read more 5 June 2026 ARCHIVIST – Protected Category Law 68/99 Department: Others Location: Siena - Italy Read more 5 June 2026 HUMAN RESOURCES INTERN Department: Others Location: Siena - Italy Read more