Principal AI Engineer — AI Solutions (Enabling Functions)
Principal AI Engineer building auditable, compliant multi-agent LLM systems for AstraZeneca's enabling functions in Barcelona.

Cambridge, GB · Founded 1913 · 5000+ staff
AstraZeneca is a science-led global healthcare company that focuses on the discovery, development and commercialisation of prescription medicines.
Roles based in: Barcelona, Blanchardstown Road North
Builds in: AI/ML
Seniority: 1 principal
Hiring engineering roles here since June 2026
Curated from live AstraZeneca PLC postings. Click any role for the full brief.
Principal AI Engineer building auditable, compliant multi-agent LLM systems for AstraZeneca's enabling functions in Barcelona.
Engineer resilient data pipelines and mesh products on Databricks/AWS to automate rare disease lab science.
Design semantic data backbone and ontologies for clinical supply labs using Databricks on AWS.
Engineer resilient data pipelines and mesh products on Databricks/AWS to automate rare disease lab science.
No longer open on AstraZeneca PLC's site. Kept for reference — saved archived roles stay in your dashboard.
Build scalable health-tech digital solutions using React, TypeScript/Node.js, AWS CDK, and GxP compliance.
Develop data pipelines for Knowledge Graph AI projects, supporting LLM applications within AstraZeneca's BioPharmaceutical domain.
Design multi-cloud AI compute services, orchestrating GPU capacity for drug discovery at AstraZeneca.
Build AI/ML tools for AstraZeneca's CAR-T and oncology discovery teams.
Build governed AI applications for AstraZeneca's global operations.
Design enterprise architecture for sustainability initiatives at AstraZeneca, shaping 1-5 year strategic roadmaps and immediate solution designs.
Lead platform engineering for scientific computing, accelerating drug discovery and patient impact at AstraZeneca.
Build AI-ready medical data foundations for AstraZeneca's global medical teams.